keeping with World Health Organisation guidelines of the assessment
of herbal medicines, Sutherlandia is generally regarded as safe
on the basis of its long history of safe use in South Africa. No
severe adverse effects are known.
Known side-effects include occasional reports of
dry mouth, occasional reports of mild diuretic effect; occasional
reports of loose stool, occasional reports of constipation. Slight
dizziness has been occasionally noted in very wasted and weak patients
(e.g. in an ill adult weighing 35kg) who take Sutherlandia without
meals this is corrected by instructing wasted patients to take the
product after meals.
Although there is a well-established traditional
use of taking Sutherlandia in pregnancy, this is not recommended
until there is further evidence of safety during pregnancy.
There were no deaths in mice given the enormous
dose of 1,500mg/kg by mouth.